BRCA Breast Cancer Screening in KL & Selangor
Breast Cancer Screening
BRCA1 testing is a genetic test that looks for mutations in the BRCA1 gene. BRCA1 and BRCA2 are genes that produce proteins involved in repairing damaged DNA in cells. With just a simple blood test and DNA analysis, doctors can identify the risk of their patient developing certain cancers.
What are BRCA1 and BRCA2?
BRCA1 and BRCA2 genes encode proteins responsible for DNA repair in our bodies, akin to instruction manuals. Each individual inherits two copies of these genes, one from each parent. However, if these genes contain harmful changes or mutations, it increases the risk of developing cancers, notably breast and ovarian cancer, often occurring at a younger age.
These genetic errors can be inherited from either parent, and if one parent carries a mutation, there is a 50% likelihood that their child will inherit it as well. These mutations are present in all cells from birth. In some cases, even if one copy of the gene is normal and the other is mutated, the normal copy can change in certain cells over time. When this occurs, these altered cells can grow uncontrollably, potentially leading to the development of cancer.
Is BRCA Testing Reliable for Breast Cancer Detection?
BRCA1 testing is generally very reliable, but it’s important to understand its limitations:
- High Accuracy: The test itself is very accurate at detecting mutations in the BRCA1 and BRCA2 gene, which we know are significant markers.
- Not 100% Predictive: Even with a positive test, it doesn’t guarantee you’ll develop cancer. There’s still a 15-20% chance of not getting cancer despite the mutation. A negative test result is also not a definitive guarantee of no risk, although it suggests a lower inherited risk.
- Focuses on Specific Mutations: The test looks for known mutations, but there may be some less common ones not identified.
Here’s an analogy: Imagine BRCA1 testing as a smoke detector for cancer risk. A positive test is like a blaring alarm, indicating a heightened risk. But just like a smoke detector doesn’t guarantee a fire, it prompts further action (investigating the source of the smoke). A negative test is like having no alarm or a silent one – peace of mind regarding inherited risk, but not eliminating all fire risk altogether.
How reduce risk of cancer if detected positive?
For women with these variants, options may include starting breast cancer screening at a younger age, more frequent screening, or using magnetic resonance imaging (MRI) in addition to mammography. However, there are no effective ovarian cancer screening methods.
Some individuals may opt for risk-reducing surgery, such as bilateral risk-reducing mastectomy to reduce the risk of breast cancer or bilateral risk-reducing salpingo-oophorectomy to reduce the risk of ovarian cancer. These surgeries have potential complications and are irreversible.
Medicines like tamoxifen and raloxifene can be used to lower the risk of breast cancer in women at increased risk, but their role in those with harmful BRCA1 or BRCA2 variants is not entirely clear. These drugs may have side effects like menopausal symptoms, blood clots, and increased cancer risk in some cases.
It’s important to note that while these measures can significantly reduce the risk of cancer, they do not guarantee prevention. Regular discussions with healthcare professionals and careful consideration of the benefits and potential harms of each option are essential for individuals with harmful BRCA1 or BRCA2 variants.
Benefits of Genetic Testing for BRCA1 and BRCA2
When the Result is Negative:
Getting a negative result from genetic testing can make people feel relieved because it means they have a lower risk of getting a certain type of cancer. They can also be happy knowing they won’t pass this risk on to their children. Plus, they might not need extra medical tests or surgeries.
When the Result is Positive:
If the test shows a positive result, it means there’s a higher risk of cancer. But this information can be useful. It helps people make smart choices about their health. They can work with doctors to keep a close eye on things or take steps to lower their cancer risk.
In both cases, genetic testing gives important information that can help people make better decisions about their health.
Why Choose Dr. Prevents for Breast Cancer Screening
Advanced Technology
We use advanced technologies and early cancer detection blood tests to provide an accurate screening and keep you informed.
Personalised Care
We are committed to providing you with clear communication and compassionate care throughout the screening process.
Available 24/7
We offer flexible scheduling options to fit your needs. Whether it's the middle of the night or a weekend, a 24-hour clinic is there for you when unexpected health issues arise.
FAQs
A small blood sample is collected from the individual. This is typically done through a standard blood draw, similar to what you might experience during a routine medical checkup.
Genetic testing for BRCA mutations is typically recommended for individuals with a strong family history of breast or ovarian cancer, especially if multiple family members have had these cancers at a young age.
Yes, BRCA mutations can be passed to the next generation. If you have a known BRCA mutation, your children may consider genetic testing as adults or earlier if recommended by a genetic counsellor, usually taking into account family history and mutation specifics.
Book An Appointment with Our Doctors!
Let's have a discussion about the Early Breast Cancer Detection test and determine if it's right for you. Our doctors will provide comprehensive information and address any concerns, ensuring you receive the highest quality of care. Take the first step towards early detection and prevention of breast cancer.
Prevention is better than cure.